KLF4 prevents epithelial to mesenchymal transition in human corneal epithelial cells via endogenous TGF-β2 suppression

INTRODUCTION: Krüppel-like factor 4 (KLF4) is considered one of the Yamanaka factors, and recently, we and others have shown that KLF4 is one of the transcription factors essential for reprogramming non-human corneal epithelial cells (HCECs) into HCECs. Since epithelial to mesenchymal transition (EM...

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Pubblicato in:Regen Ther
Autori principali: Fujimoto, Satoko, Hayashi, Ryuhei, Hara, Susumu, Sasamoto, Yuzuru, Harrington, Jodie, Tsujikawa, Motokazu, Nishida, Kohji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Japanese Society for Regenerative Medicine 2019
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6745437/
https://ncbi.nlm.nih.gov/pubmed/31538102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reth.2019.08.003
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