Human iPS cells engender corneal epithelial stem cells with holoclone-forming capabilities

Human induced pluripotent stem cells (hiPSCs) can generate a multiplicity of organoids, yet no compelling evidence currently exists as to whether or not these contain tissue-specific, holoclone-forming stem cells. Here, we show that a subpopulation of cells in a hiPSC-derived corneal epithelial cell...

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Publicat a:iScience
Autors principals: Watanabe, Shinya, Hayashi, Ryuhei, Sasamoto, Yuzuru, Tsujikawa, Motokazu, Ksander, Bruce R., Frank, Markus H., Quantock, Andrew J., Frank, Natasha Y., Nishida, Kohji
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233200/
https://ncbi.nlm.nih.gov/pubmed/34195566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102688
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