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Attacking Cancer’s Achilles Heel: Antagonism of Anti-Apoptotic BCL-2 Family Members
Malignant cells routinely violate cellular checkpoints that should initiate cell death in normal cells by triggering pro-apoptotic members of the BCL-2 family of proteins. To escape such death inducing signals, cancer cells often select for up regulation of anti-apoptotic BCL-2 family members includ...
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| Udgivet i: | FEBS J |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4761532/ https://ncbi.nlm.nih.gov/pubmed/26293580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13472 |
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