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Attacking Cancer’s Achilles Heel: Antagonism of Anti-Apoptotic BCL-2 Family Members

Malignant cells routinely violate cellular checkpoints that should initiate cell death in normal cells by triggering pro-apoptotic members of the BCL-2 family of proteins. To escape such death inducing signals, cancer cells often select for up regulation of anti-apoptotic BCL-2 family members includ...

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Detaylı Bibliyografya
Yayımlandı:FEBS J
Yazar: Opferman, Joseph T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761532/
https://ncbi.nlm.nih.gov/pubmed/26293580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13472
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