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Control of Spine Maturation and Pruning through ProBDNF Synthesized and Released in Dendrites

Excess synapses formed during early postnatal development are pruned over an extended period, while the remaining synapses mature. Synapse pruning is critical for activity-dependent refinement of neuronal connections and its dysregulation has been found in neurodevelopmental disorders such as autism...

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Bibliographic Details
Published in:Mol Cell Neurosci
Main Authors: Orefice, Lauren L., Shih, Chien-Cheng, Xu, Haifei, Waterhouse, Emily G., Xu, Baoji
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761458/
https://ncbi.nlm.nih.gov/pubmed/26705735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2015.12.010
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