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Control of Spine Maturation and Pruning through ProBDNF Synthesized and Released in Dendrites
Excess synapses formed during early postnatal development are pruned over an extended period, while the remaining synapses mature. Synapse pruning is critical for activity-dependent refinement of neuronal connections and its dysregulation has been found in neurodevelopmental disorders such as autism...
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| Published in: | Mol Cell Neurosci |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4761458/ https://ncbi.nlm.nih.gov/pubmed/26705735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2015.12.010 |
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