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On efficient and accurate calculation of significance p-values for sequence kernel association testing of variant set
The objective of this paper is to discuss and develop alternative computational methods to accurately and efficiently calculate significance p-values for the commonly used sequence kernel association test (SKAT) and adaptive sum of SKAT and burden test (SKAT-O) for variant set association. We show t...
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| Publicado no: | Ann Hum Genet |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4761292/ https://ncbi.nlm.nih.gov/pubmed/26757198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ahg.12144 |
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