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On sample size and power calculation for variant set-based association tests

Sample size and power calculations are an important part of designing new sequence-based association studies. In this paper, we explore an efficient and accurate approach to computing sample size and power (particularly at small significance level, e.g., 10(−6)) for the sequence kernel association t...

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Detalhes bibliográficos
Publicado no:Ann Hum Genet
Main Authors: Wu, Baolin, Pankow, James S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761288/
https://ncbi.nlm.nih.gov/pubmed/26831402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ahg.12147
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