Involvement of transglutaminase 2 and voltage‐gated potassium channels in cystamine vasodilatation in rat mesenteric small arteries

BACKGROUND AND PURPOSE: Vasodilatation may contribute to the neuroprotective and vascular anti‐remodelling effect of the tissue transglutaminase 2 (TG2) inhibitor cystamine. Here, we hypothesized that inhibition of TG2 followed by blockade of smooth muscle calcium entry and/or inhibition of Rho kina...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Engholm, Morten, Pinilla, Estéfano, Mogensen, Susie, Matchkov, Vladimir, Hedegaard, Elise Røge, Chen, Hua, Mulvany, Michael J, Simonsen, Ulf
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761098/
https://ncbi.nlm.nih.gov/pubmed/26603619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13393
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