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Cystamine and cysteamine as inhibitors of transglutaminase activity in vivo

Cystamine is commonly used as a transglutaminase inhibitor. This disulphide undergoes reduction in vivo to the aminothiol compound, cysteamine. Thus, the mechanism by which cystamine inhibits transglutaminase activity in vivo could be due to either cystamine or cysteamine, which depends on the local...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Jeitner, Thomas M., Pinto, John T., Cooper, Arthur J.L.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6123069/
https://ncbi.nlm.nih.gov/pubmed/30054429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20180691
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