Proinflammatory signal suppresses proliferation and shifts macrophage metabolism from Myc-dependent to HIF1α-dependent

As a phenotypically plastic cellular population, macrophages change their physiology in response to environmental signals. Emerging evidence suggests that macrophages are capable of tightly coordinating their metabolic programs to adjust their immunological and bioenergetic functional properties, as...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Liu, Lingling, Lu, Yun, Martinez, Jennifer, Bi, Yujing, Lian, Gaojian, Wang, Tingting, Milasta, Sandra, Wang, Jian, Yang, Mao, Liu, Guangwei, Green, Douglas R., Wang, Ruoning
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760828/
https://ncbi.nlm.nih.gov/pubmed/26811453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1518000113
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