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Control of APC/C-dependent ubiquitin chain elongation by reversible phosphorylation
Most metazoan E3 ligases contain a signature RING domain that promotes the transfer of ubiquitin from the active site of E2 conjugating enzymes to lysine residues in substrates. Although these RING-E3s depend on E2 enzymes for catalysis, how they turn on their E2s at the right time and place remains...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4760819/ https://ncbi.nlm.nih.gov/pubmed/26811472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522423113 |
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