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The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2
Ubiquitin chains of different topologies trigger distinct functional consequences, including protein degradation and reorganization of complexes. The assembly of most ubiquitin chains is promoted by E2s, yet how these enzymes achieve linkage specificity is poorly understood. We have discovered that...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3072108/ https://ncbi.nlm.nih.gov/pubmed/21376237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.01.035 |
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