Cell–cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis

Collective cell responses to exogenous cues depend on cell–cell interactions. In principle, these can result in enhanced sensitivity to weak and noisy stimuli. However, this has not yet been shown experimentally, and little is known about how multicellular signal processing modulates single-cell sen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Ellison, David, Mugler, Andrew, Brennan, Matthew D., Lee, Sung Hoon, Huebner, Robert J., Shamir, Eliah R., Woo, Laura A., Kim, Joseph, Amar, Patrick, Nemenman, Ilya, Ewald, Andrew J., Levchenko, Andre
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2016
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760786/
https://ncbi.nlm.nih.gov/pubmed/26792522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516503113
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