Cell–cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis

Collective cell responses to exogenous cues depend on cell–cell interactions. In principle, these can result in enhanced sensitivity to weak and noisy stimuli. However, this has not yet been shown experimentally, and little is known about how multicellular signal processing modulates single-cell sen...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ellison, David, Mugler, Andrew, Brennan, Matthew D., Lee, Sung Hoon, Huebner, Robert J., Shamir, Eliah R., Woo, Laura A., Kim, Joseph, Amar, Patrick, Nemenman, Ilya, Ewald, Andrew J., Levchenko, Andre
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760786/
https://ncbi.nlm.nih.gov/pubmed/26792522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516503113
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