Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling

Posttranslational modifications are central to the spatial and temporal regulation of protein function. Among others, phosphorylation and ubiquitylation are known to regulate proximal T-cell receptor (TCR) signaling. Here we used a systematic and unbiased approach to uncover deubiquitylating enzymes...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Jahan, Akhee S., Lestra, Maxime, Swee, Lee Kim, Fan, Ying, Lamers, Mart M., Tafesse, Fikadu G., Theile, Christopher S., Spooner, Eric, Bruzzone, Roberto, Ploegh, Hidde L., Sanyal, Sumana
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760780/
https://ncbi.nlm.nih.gov/pubmed/26811477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521763113
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