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The activity of myeloid cell-specific VHH immunotoxins is target-, epitope-, subset- and organ dependent
The central role of myeloid cells in driving autoimmune diseases and cancer has raised interest in manipulating their function or depleting them for therapeutic benefits. To achieve this, antibodies are used to antagonize differentiation, survival and polarization signals or to kill target cells, fo...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5738442/ https://ncbi.nlm.nih.gov/pubmed/29263417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17948-0 |
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