The Development of a Recombinant scFv Monoclonal Antibody Targeting Canine CD20 for Use in Comparative Medicine

Monoclonal antibodies are leading agents for therapeutic treatment of human diseases, but are limited in use by the paucity of clinically relevant models for validation. Sporadic canine tumours mimic the features of some human equivalents. Developing canine immunotherapeutics can be an approach for...

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Veröffentlicht in:PLoS One
Hauptverfasser: Jain, Saurabh, Aresu, Luca, Comazzi, Stefano, Shi, Jianguo, Worrall, Erin, Clayton, John, Humphries, William, Hemmington, Sandra, Davis, Paul, Murray, Euan, Limeneh, Asmare A., Ball, Kathryn, Ruckova, Eva, Muller, Petr, Vojtesek, Borek, Fahraeus, Robin, Argyle, David, Hupp, Ted R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760772/
https://ncbi.nlm.nih.gov/pubmed/26894679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148366
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