Using Gelatin Nanoparticle Mediated Intranasal Delivery of Neuropeptide Substance P to Enhance Neuro-Recovery in Hemiparkinsonian Rats

PURPOSE: Intranasal administration of phospholipid-based gelatin nanoparticles (GNP) was prepared to investigate the neuro-recovery effects of neuropeptide Substance P (SP) on hemiparkinsonian rats. METHODS: The SP-loaded gelatin nanoparticles (SP-GNP) were prepared by a water-in-water emulsion meth...

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Udgivet i:PLoS One
Main Authors: Zhao, Ying-Zheng, Jin, Rong-Rong, Yang, Wei, Xiang, Qi, Yu, Wen-Ze, Lin, Qian, Tian, Fu-Rong, Mao, Kai-Li, Lv, Chuan-Zhu, Wáng, Yi-Xiáng J., Lu, Cui-Tao
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760767/
https://ncbi.nlm.nih.gov/pubmed/26894626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148848
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