Using Gelatin Nanoparticle Mediated Intranasal Delivery of Neuropeptide Substance P to Enhance Neuro-Recovery in Hemiparkinsonian Rats.

PURPOSE:Intranasal administration of phospholipid-based gelatin nanoparticles (GNP) was prepared to investigate the neuro-recovery effects of neuropeptide Substance P (SP) on hemiparkinsonian rats. METHODS:The SP-loaded gelatin nanoparticles (SP-GNP) were prepared by a water-in-water emulsion method...

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Main Authors: Ying-Zheng Zhao, Rong-Rong Jin, Wei Yang, Qi Xiang, Wen-Ze Yu, Qian Lin, Fu-Rong Tian, Kai-Li Mao, Chuan-Zhu Lv, Yi-Xiáng J Wáng, Cui-Tao Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2016-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4760767?pdf=render
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