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Rosiglitazone Promotes Bone Marrow Adipogenesis to Impair Myelopoiesis under Stress

OBJECTIVE: The therapeutic use of thiazolidinediones (TZDs) causes unwanted hematological side effects, although the underlying mechanisms of these effects are poorly understood. This study tests the hypothesis that rosiglitazone impairs the maintenance and differentiation of hematopoietic stem/prog...

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Publicat a:PLoS One
Autors principals: Lu, Wenyi, Wang, Weimin, Wang, Shujuan, Feng, Yonghuai, Liu, Kaiyan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760757/
https://ncbi.nlm.nih.gov/pubmed/26895498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149543
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