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Rosiglitazone Promotes Bone Marrow Adipogenesis to Impair Myelopoiesis under Stress

OBJECTIVE: The therapeutic use of thiazolidinediones (TZDs) causes unwanted hematological side effects, although the underlying mechanisms of these effects are poorly understood. This study tests the hypothesis that rosiglitazone impairs the maintenance and differentiation of hematopoietic stem/prog...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lu, Wenyi, Wang, Weimin, Wang, Shujuan, Feng, Yonghuai, Liu, Kaiyan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760757/
https://ncbi.nlm.nih.gov/pubmed/26895498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149543
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