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Lipoprotein Lipase Deficiency Impairs Bone Marrow Myelopoiesis and Reduces Circulating Monocyte Levels

OBJECTIVES: Tissue macrophages induce and perpetuate pro-inflammatory responses, thereby promoting metabolic and cardiovascular disease. Lipoprotein lipase (LpL), the rate-limiting enzyme in blood triglyceride (TG) catabolism, is expressed by macrophages in atherosclerotic plaques. We questioned whe...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Chang, Chuchun L., Garcia-Arcos, Itsaso, Nyrén, Rakel, Olivecrona, Gunilla, Kim, Ji Young, Hu, Yunying, Agrawal, Rishi R., Murphy, Andrew J., Goldberg, Ira J., Deckelbaum, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823779/
https://ncbi.nlm.nih.gov/pubmed/29371243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310607
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