Yap and Taz play a crucial role in neural crest-derived craniofacial development

The role of the Hippo signaling pathway in cranial neural crest (CNC) development is poorly understood. We used the Wnt1(Cre) and Wnt1(Cre2SOR) drivers to conditionally ablate both Yap and Taz in the CNC of mice. When using either Cre driver, Yap and Taz deficiency in the CNC resulted in enlarged, h...

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Dades bibliogràfiques
Publicat a:Development
Autors principals: Wang, Jun, Xiao, Yang, Hsu, Chih-Wei, Martinez-Traverso, Idaliz M., Zhang, Min, Bai, Yan, Ishii, Mamoru, Maxson, Robert E., Olson, Eric N., Dickinson, Mary E., Wythe, Joshua D., Martin, James F.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760309/
https://ncbi.nlm.nih.gov/pubmed/26718006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.126920
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