Yap and Taz play a crucial role in neural crest-derived craniofacial development

The role of the Hippo signaling pathway in cranial neural crest (CNC) development is poorly understood. We used the Wnt1(Cre) and Wnt1(Cre2SOR) drivers to conditionally ablate both Yap and Taz in the CNC of mice. When using either Cre driver, Yap and Taz deficiency in the CNC resulted in enlarged, h...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Wang, Jun, Xiao, Yang, Hsu, Chih-Wei, Martinez-Traverso, Idaliz M., Zhang, Min, Bai, Yan, Ishii, Mamoru, Maxson, Robert E., Olson, Eric N., Dickinson, Mary E., Wythe, Joshua D., Martin, James F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760309/
https://ncbi.nlm.nih.gov/pubmed/26718006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.126920
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