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The role of the Annexin-A1/FPR2 system in the regulation of mast cell degranulation provoked by compound 48/80 and in the inhibitory action of nedocromil

1. We investigated the role of Annexin (ANX)-A1 and its receptor, ALX/FPR2, in the regulation of mast cell degranulation produced by compound 48/80. 2. Both human cord-blood derived mast cells (CBDMCs) and murine bone marrow derived mast cells (BMDMCs) release phosphorylated ANX-A1 during treatment...

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Bibliographic Details
Published in:Int Immunopharmacol
Main Authors: Sinniah, Ajantha, Yazid, Samia, Perretti, M., Solito, Egle, Flower, R.J.
Format: Artigo
Language:Inglês
Published: Elsevier Science 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760273/
https://ncbi.nlm.nih.gov/pubmed/26803520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2016.01.003
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