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ROMA: Representation and Quantification of Module Activity from Target Expression Data

In many analyses of high-throughput data in systems biology, there is a need to quantify the activity of a set of genes in individual samples. A typical example is the case where it is necessary to estimate the activity of a transcription factor (which is often not directly measurable) from the expr...

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Bibliographic Details
Published in:Front Genet
Main Authors: Martignetti, Loredana, Calzone, Laurence, Bonnet, Eric, Barillot, Emmanuel, Zinovyev, Andrei
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760130/
https://ncbi.nlm.nih.gov/pubmed/26925094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00018
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