Rapid expansion of preexisting nonleukemic hematopoietic clones frequently follows induction therapy for de novo AML

There is interest in using leukemia-gene panels and next-generation sequencing to assess acute myelogenous leukemia (AML) response to induction chemotherapy. Studies have shown that patients with AML in morphologic remission may continue to have clonal hematopoiesis with populations closely related...

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Publicado en:Blood
Autores principales: Wong, Terrence N., Miller, Christopher A., Klco, Jeffery M., Petti, Allegra, Demeter, Ryan, Helton, Nichole M., Li, Tiandao, Fulton, Robert S., Heath, Sharon E., Mardis, Elaine R., Westervelt, Peter, DiPersio, John F., Walter, Matthew J., Welch, John S., Graubert, Timothy A., Wilson, Richard K., Ley, Timothy J., Link, Daniel C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2016
Materias:
Myeloid Neoplasia
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760092/
https://ncbi.nlm.nih.gov/pubmed/26631115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-10-677021
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