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Neutrophils, platelets, and inflammatory pathways at the nexus of sickle cell disease pathophysiology

Sickle cell disease (SCD) is a severe genetic blood disorder characterized by hemolytic anemia, episodic vaso-occlusion, and progressive organ damage. Current management of the disease remains symptomatic or preventative. Specific treatment targeting major complications such as vaso-occlusion is sti...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Zhang, Dachuan, Xu, Chunliang, Manwani, Deepa, Frenette, Paul S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760086/
https://ncbi.nlm.nih.gov/pubmed/26758915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-09-618538
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