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Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease
Sickle cell disease (SCD) is characterized by recurring episodes of vascular occlusion in which neutrophil activation plays a major role. The disease is associated with chronic hemolysis with elevated cell-free hemoglobin and heme. The ensuing depletion of heme scavenger proteins leads to nonspecifi...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society of Hematology
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4055928/ https://ncbi.nlm.nih.gov/pubmed/24620350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-10-529982 |
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