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Vaso-occlusion in sickle cell disease: pathophysiology and novel targeted therapies
Recurrent and unpredictable episodes of vaso-occlusion are the hallmark of sickle cell disease. Symptomatic management and prevention of these events using the fetal hemoglobin–reactivating agent hydroxyurea are currently the mainstay of treatment. Discoveries over the past 2 decades have highlighte...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3854110/ https://ncbi.nlm.nih.gov/pubmed/24052549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-05-498311 |
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