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Prolonged pemetrexed pretreatment augments persistence of cisplatin-induced DNA damage and eliminates resistant lung cancer stem-like cells associated with EMT

BACKGROUND: Lung cancer is the leading cause of cancer-related mortality, and new therapeutic options are urgently needed. Non-small cell lung cancer (NSCLC) accounts for approximately 85 % of all lung cancers, with the current standard regimen of care for NSCLC including chemotherapy with pemetrexe...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:BMC Cancer
Main Authors: Tièche, Colin Charles, Peng, Ren-Wang, Dorn, Patrick, Froment, Laurène, Schmid, Ralph Alexander, Marti, Thomas Michael
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759918/
https://ncbi.nlm.nih.gov/pubmed/26895954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2117-4
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