Development of 5‘ LTR DNA methylation of latent HIV-1 provirus in cell line models and in long-term-infected individuals

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) latency represents the major barrier to virus eradication in infected individuals because cells harboring latent HIV-1 provirus are not affected by current antiretroviral therapy (ART). We previously demonstrated that DNA methylation of HIV-1 l...

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Bibliografski detalji
Izdano u:Clin Epigenetics
Glavni autori: Trejbalová, Kateřina, Kovářová, Denisa, Blažková, Jana, Machala, Ladislav, Jilich, David, Weber, Jan, Kučerová, Dana, Vencálek, Ondřej, Hirsch, Ivan, Hejnar, Jiří
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759744/
https://ncbi.nlm.nih.gov/pubmed/26900410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0185-6
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