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Quantitative prediction and clinical evaluation of an unexplored herb–drug interaction mechanism in healthy volunteers
Quantitative prediction of herb–drug interaction risk remains challenging. A quantitative framework to assess a potential interaction was used to evaluate a mechanism not previously tested in humans. The semipurified milk thistle product, silibinin, was selected as an exemplar herbal product inhibit...
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| Publié dans: | CPT Pharmacometrics Syst Pharmacol |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4759704/ https://ncbi.nlm.nih.gov/pubmed/26904384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12047 |
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