A DNA aptamer recognising a malaria protein biomarker can function as part of a DNA origami assembly

DNA aptamers have potential for disease diagnosis and as therapeutics, particularly when interfaced with programmable molecular technology. Here we have combined DNA aptamers specific for the malaria biomarker Plasmodium falciparum lactate dehydrogenase (PfLDH) with a DNA origami scaffold. Twelve ap...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Godonoga, Maia, Lin, Ting-Yu, Oshima, Azusa, Sumitomo, Koji, Tang, Marco S. L., Cheung, Yee-Wai, Kinghorn, Andrew B., Dirkzwager, Roderick M., Zhou, Cunshan, Kuzuya, Akinori, Tanner, Julian A., Heddle, Jonathan G.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759581/
https://ncbi.nlm.nih.gov/pubmed/26891622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21266
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