A DNA aptamer recognising a malaria protein biomarker can function as part of a DNA origami assembly

DNA aptamers have potential for disease diagnosis and as therapeutics, particularly when interfaced with programmable molecular technology. Here we have combined DNA aptamers specific for the malaria biomarker Plasmodium falciparum lactate dehydrogenase (PfLDH) with a DNA origami scaffold. Twelve ap...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Godonoga, Maia, Lin, Ting-Yu, Oshima, Azusa, Sumitomo, Koji, Tang, Marco S. L., Cheung, Yee-Wai, Kinghorn, Andrew B., Dirkzwager, Roderick M., Zhou, Cunshan, Kuzuya, Akinori, Tanner, Julian A., Heddle, Jonathan G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759581/
https://ncbi.nlm.nih.gov/pubmed/26891622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21266
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