Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression

Macrophages in the arterial intima sustain chronic inflammation during atherogenesis. Under hypercholesterolemic conditions murine Ly6C(high) monocytes surge in the blood and spleen, infiltrate nascent atherosclerotic plaques, and differentiate into macrophages that proliferate locally as disease pr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Basic Res Cardiol
Main Authors: Lindau, Alexandra, Härdtner, Carmen, Hergeth, Sonja P., Blanz, Kelly Daryll, Dufner, Bianca, Hoppe, Natalie, Anto-Michel, Nathaly, Kornemann, Jan, Zou, Jiadai, Gerhardt, Louisa M. S., Heidt, Timo, Willecke, Florian, Geis, Serjosha, Stachon, Peter, Wolf, Dennis, Libby, Peter, Swirski, Filip K., Robbins, Clinton S., McPheat, William, Hawley, Shaun, Braddock, Martin, Gilsbach, Ralf, Hein, Lutz, von zur Mühlen, Constantin, Bode, Christoph, Zirlik, Andreas, Hilgendorf, Ingo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Original Contribution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4759214/
https://ncbi.nlm.nih.gov/pubmed/26891724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-016-0535-8
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados