A Polymorphism in the FGFR4 Gene is associated with Risk of Neuroblastoma and Altered Receptor Degradation

BACKGROUND: Outcomes for children with high-risk neuroblastoma are poor, and improved understanding of the mechanisms underlying pathogenesis, recurrence and treatment resistance will lead to improved outcomes. Aberrant growth factor receptor expression and receptor tyrosine kinase signaling are ass...

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Veröffentlicht in:J Pediatr Hematol Oncol
Hauptverfasser: Whittle, Sarah B., Reyes, Sahily, Du, Melissa, Gireud, Monica, Zhang, Linna, Woodfield, Sarah E., Ittmann, Michael, Scheurer, Michael E., Bean, Andrew J., Zage, Peter E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758892/
https://ncbi.nlm.nih.gov/pubmed/26840079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPH.0000000000000506
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