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A Polymorphism in the FGFR4 Gene is associated with Risk of Neuroblastoma and Altered Receptor Degradation

BACKGROUND: Outcomes for children with high-risk neuroblastoma are poor, and improved understanding of the mechanisms underlying pathogenesis, recurrence and treatment resistance will lead to improved outcomes. Aberrant growth factor receptor expression and receptor tyrosine kinase signaling are ass...

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Bibliografske podrobnosti
izdano v:J Pediatr Hematol Oncol
Main Authors: Whittle, Sarah B., Reyes, Sahily, Du, Melissa, Gireud, Monica, Zhang, Linna, Woodfield, Sarah E., Ittmann, Michael, Scheurer, Michael E., Bean, Andrew J., Zage, Peter E.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758892/
https://ncbi.nlm.nih.gov/pubmed/26840079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPH.0000000000000506
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