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Identification of Thiotetronic Acid Antibiotic Biosynthetic Pathways by Target-directed Genome Mining

Recent genome sequencing efforts have led to the rapid accumulation of uncharacterized or “orphaned” secondary metabolic biosynthesis gene clusters (BGCs) in public databases. This increase in DNA-sequenced big data has given rise to significant challenges in the applied field of natural product gen...

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Publicat a:ACS Chem Biol
Autors principals: Tang, Xiaoyu, Li, Jie, Millán-Aguiñaga, Natalie, Zhang, Jia Jia, O'Neill, Ellis C., Ugalde, Juan A., Jensen, Paul R., Mantovani, Simone M., Moore, Bradley S.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758359/
https://ncbi.nlm.nih.gov/pubmed/26458099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00658
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