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Assessing Cell-to-Cell DNA Methylation Variability on Individual Long Reads

Understanding cell-to-cell variability in cytosine methylation is essential for understanding cellular perturbation and its molecular machinery. However, conventional methylation studies have focused on the differences in the average levels between cell types while overlooking methylation heterogene...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Qu, Wei, Tsukahara, Tatsuya, Nakamura, Ryohei, Yurino, Hideaki, Hashimoto, Shin-ichi, Tsuji, Shoji, Takeda, Hiroyuki, Morishita, Shinichi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758075/
https://ncbi.nlm.nih.gov/pubmed/26888466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21317
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