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Assessing Cell-to-Cell DNA Methylation Variability on Individual Long Reads

Understanding cell-to-cell variability in cytosine methylation is essential for understanding cellular perturbation and its molecular machinery. However, conventional methylation studies have focused on the differences in the average levels between cell types while overlooking methylation heterogene...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Qu, Wei, Tsukahara, Tatsuya, Nakamura, Ryohei, Yurino, Hideaki, Hashimoto, Shin-ichi, Tsuji, Shoji, Takeda, Hiroyuki, Morishita, Shinichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758075/
https://ncbi.nlm.nih.gov/pubmed/26888466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21317
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