Diabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation in Mice

Endocrine and exocrine pancreas tissues are both derived from the posterior foregut endoderm, however, the interdependence of these two cell types during their formation is not well understood. In this study, we generated mutant mice, in which the exocrine tissue is hypoplastic, in order to reveal a...

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Udgivet i:Sci Rep
Main Authors: Kodama, Sota, Nakano, Yasuhiro, Hirata, Koji, Furuyama, Kenichiro, Horiguchi, Masashi, Kuhara, Takeshi, Masui, Toshihiko, Kawaguchi, Michiya, Gannon, Maureen, Wright, Christopher V. E., Uemoto, Shinji, Kawaguchi, Yoshiya
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758062/
https://ncbi.nlm.nih.gov/pubmed/26887806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21211
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