Exocrine tissue-driven TFF2 prevents apoptotic cell death of endocrine lineage during pancreas organogenesis

During embryogenesis, exocrine and endocrine pancreatic tissues are formed in distinct regions within the branched ductal structure in mice. We previously reported that exocrine-specific inactivation of Pdx1 by Elastase-Cre caused not only hypoplastic exocrine formation but also substantial endocrin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Hirata, Koji, Kodama, Sota, Nakano, Yasuhiro, Minaki-Nakagawa, Yasuko, Aoyama, Yoshiki, Sakikubo, Morito, Goto, Toshihiko, Yoshida, Masahiro, Masui, Toshihiko, Yamamoto, Takuya, Uemoto, Shinji, Kawaguchi, Yoshiya
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367380/
https://ncbi.nlm.nih.gov/pubmed/30733468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38062-9
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