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TNFα induces co-trafficking of TRPV1/TRPA1 in VAMP1-containing vesicles to the plasmalemma via Munc18–1/syntaxin1/SNAP-25 mediated fusion

Transient receptor potential (TRP) A1 and V1 channels relay sensory signals, yet little is known about their transport to the plasmalemma during inflammation. Herein, TRPA1 and TRPV1 were found on vesicles containing calcitonin gene-related peptide (CGRP), accumulated at sites of exo- and endo-cytos...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Meng, Jianghui, Wang, Jiafu, Steinhoff, Martin, Dolly, James Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758037/
https://ncbi.nlm.nih.gov/pubmed/26888187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21226
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