Syntaxin 4, VAMP2, and/or VAMP3/cellubrevin are functional target membrane and vesicle SNAP receptors for insulin-stimulated GLUT4 translocation in adipocytes.

Introduction of the cytoplasmic domain of syntaxin 4, using either recombinant vaccinia virus or single-cell microinjection, resulted in an inhibition of insulin-stimulated GLUT4 but not GLUT1 translocation to the plasma membrane. This was specific for syntaxin 4, since neither the expression of syn...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Olson, A L, Knight, J B, Pessin, J E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC232091/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9111311/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.5.2425
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