Early Golgi Abnormalities and Neurodegeneration upon Loss of Presynaptic Proteins Munc18-1, Syntaxin-1, or SNAP-25

The loss of presynaptic proteins Munc18-1, syntaxin-1, or SNAP-25 is known to produce cell death, but the underlying features have not been compared experimentally. Here, we investigated these features in cultured mouse CNS and DRG neurons. Side-by-side comparisons confirmed massive cell death, befo...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Santos, Tatiana C., Wierda, Keimpe, Broeke, Jurjen H., Toonen, Ruud F., Verhage, Matthijs
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2017
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596660/
https://ncbi.nlm.nih.gov/pubmed/28348137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3352-16.2017
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