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Munc18-1 expression levels control synapse recovery by regulating readily releasable pool size

Prompt recovery after intense activity is an essential feature of most mammalian synapses. Here we show that synapses with reduced expression of the presynaptic gene munc18-1 suffer from increased depression during intense stimulation at glutamatergic, GABAergic, and neuromuscular synapses. Converse...

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Bibliografiset tiedot
Päätekijät: Toonen, Ruud F. G., Wierda, Keimpe, Sons, Michèle S., de Wit, Heidi, Cornelisse, L. Niels, Brussaard, Arjen, Plomp, Jaap J., Verhage, Matthijs
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2006
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838751/
https://ncbi.nlm.nih.gov/pubmed/17110441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608507103
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