Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase

Choline is an essential nutrient for all living cells and is produced extracellularly by sequential degradation of phosphatidylcholine (PC). However, little is known about how choline is produced extracellularly. Here, we report that ENPP6, a choline-specific phosphodiesterase, hydrolyzes glyceropho...

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Udgivet i:Sci Rep
Main Authors: Morita, Junko, Kano, Kuniyuki, Kato, Kazuki, Takita, Hiroyuki, Sakagami, Hideki, Yamamoto, Yasuo, Mihara, Emiko, Ueda, Hirofumi, Sato, Takanao, Tokuyama, Hidetoshi, Arai, Hiroyuki, Asou, Hiroaki, Takagi, Junichi, Ishitani, Ryuichiro, Nishimasu, Hiroshi, Nureki, Osamu, Aoki, Junken
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757880/
https://ncbi.nlm.nih.gov/pubmed/26888014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20995
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