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Structural and biochemical characterization of an RNA/DNA binding motif in the N-terminal domain of RecQ4 helicases

The RecQ4 helicase belongs to the ubiquitous RecQ family but its exact role in the cell is not completely understood. In addition to the helicase domain, RecQ4 has a unique N-terminal part that is essential for viability and is constituted by a region homologous to the yeast Sld2 replication initiat...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Marino, Francesca, Mojumdar, Aditya, Zucchelli, Chiara, Bhardwaj, Amit, Buratti, Emanuele, Vindigni, Alessandro, Musco, Giovanna, Onesti, Silvia
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757822/
https://ncbi.nlm.nih.gov/pubmed/26888063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21501
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