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Structural and biochemical characterization of an RNA/DNA binding motif in the N-terminal domain of RecQ4 helicases

The RecQ4 helicase belongs to the ubiquitous RecQ family but its exact role in the cell is not completely understood. In addition to the helicase domain, RecQ4 has a unique N-terminal part that is essential for viability and is constituted by a region homologous to the yeast Sld2 replication initiat...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Marino, Francesca, Mojumdar, Aditya, Zucchelli, Chiara, Bhardwaj, Amit, Buratti, Emanuele, Vindigni, Alessandro, Musco, Giovanna, Onesti, Silvia
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757822/
https://ncbi.nlm.nih.gov/pubmed/26888063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21501
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