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Macrophage infiltration and alternative activation during wound healing promote MEK1-induced skin carcinogenesis

Macrophages are essential for the progression and maintenance of many cancers, but their role during the earliest stages of tumor formation is unclear. To test this, we used a previously described transgenic mouse model of wound-induced skin tumorigenesis, in which expression of constitutively activ...

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Podrobná bibliografie
Vydáno v:Cancer Res
Hlavní autoři: Weber, Christine, Telerman, Stephanie B., Reimer, Andreas S., Sequeira, Ines, Liakath-Ali, Kifayathullah, Arwert, Esther N., Watt, Fiona M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757739/
https://ncbi.nlm.nih.gov/pubmed/26754935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-3676
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