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Macrophage infiltration and alternative activation during wound healing promote MEK1-induced skin carcinogenesis

Macrophages are essential for the progression and maintenance of many cancers, but their role during the earliest stages of tumor formation is unclear. To test this, we used a previously described transgenic mouse model of wound-induced skin tumorigenesis, in which expression of constitutively activ...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Weber, Christine, Telerman, Stephanie B., Reimer, Andreas S., Sequeira, Ines, Liakath-Ali, Kifayathullah, Arwert, Esther N., Watt, Fiona M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757739/
https://ncbi.nlm.nih.gov/pubmed/26754935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-3676
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